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KMID : 0363220140520040264
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Korean Journal of Dermatology
2014 Volume.52 No. 4 p.264 ~ p.268
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Three Cases of Generalized Granuloma Annulare in Infancy Following Bacillus Calmette-Guerin Vaccination
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Kim Seo-Wan
Kong Tae-Seok
Han Tae-Young
Lee Hyun-Kyung
Son Sook-Ja
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Abstract
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Generalized granuloma annulare is a rare benign granulomatous dermatosis characterized by disseminated necrobioticdermal papules forming an annular or nonannular configuration. It usually occurs in adults and rarely affects infants. Histologically, it presents as a lymphohistiocytic granuloma associated with varying degrees of connective tissue degeneration. Clinical associations between generalized granuloma annulare and diabetes mellitus, thyroid disease,malignancy, infection, and vaccination have been reported. There are a few cases reports of generalized granulomaannulare associated with Bacillus Calmette-Guerin (BCG) vaccination. Herein, we report three cases of generalizedgranuloma annulare following BCG vaccination in infants.
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KEYWORD
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BCG vaccine, Granuloma annulare, Infant
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